Anti-gamma haemolysin as a diagnostic test in staphylococcal osteomyelitis

Anti-gamma haemolysin as a diagnostic test in staphylococcal osteomyelitis.

The anti-alpha-haemolysin test is widely used in the diagnosis of staphylococcal osteomyelitis. An additional test would be welcomed because raised antibodies to this antigen are not seen in all proven cases. This communication reports that anti-gamma-lysin was present in the serum of most of the 19 patients with proven staphylococcal osteomyelitis studied here. In two cases followed up after c...

The clinical evaluation of staphylococcal anti-alpha haemolysin titres in patients' sera.

a haemolysin and the pathogenicity of Staphylococcus aureus has long been a matter for discussion. Christie, North, and Parkin (1946) stated that the production of a haemolysin is essential for full pathogenicity, and that coagulase-positive strains which produced no a haemolysin might be regarded as non-pathogenic. Marks (1952) found a close correlation between pathogenicity and the production...

Saline test for streptococcal haemolysin.

Ceftriaxone therapy for staphylococcal osteomyelitis: a review.

Ceftriaxone, although less active than standard antistaphylococcal agents, is potentially useful in the treatment of osteomyelitis. Thirty-one patients with osteomyelitis due to Staphylococcus aureus were identified, 22 of whom were treated with ceftriaxone and 9 with other agents. Of those patients treated with ceftriaxone, 17 were cured; all treatment failures were associated with chronic ost...

Chronic staphylococcal osteomyelitis: an experimental model.

Chronic osteomyelitis continues to be a serious clinical problem. For example, despite antibiotic treatment, chronic osteomyelitis has been observed to develop in 15 to 29 percent of patients with acute hematogenous osteomyelitis (1, 2). Chronic osteomyelitis has been noted to develop with greater frequency in patients with osteomyelitis secondary to postoperative infection, i.e., particularly ...